Gene

tafazzin

ID
ZDB-GENE-030131-684
Name
tafazzin, phospholipid-lysophospholipid transacylase
Symbol
tafazzin Nomenclature History
Previous Names
  • taz
  • wu:fb39f12
  • zgc:91803
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have O-acyltransferase activity. Involved in heart looping and positive regulation of heart contraction. Predicted to localize to integral component of mitochondrial outer membrane. Used to study Barth syndrome and visceral heterotaxy. Human ortholog(s) of this gene implicated in Barth syndrome and dilated cardiomyopathy. Is expressed in endoderm; head; immature eye; pericardial region; and post-vent region. Orthologous to human TAZ (tafazzin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tafazzin Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Barth syndrome Alliance Barth syndrome 302060
Associated With tafazzin Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002123 Phospholipid/glycerol acyltransferase
Family IPR000872 Tafazzin
Domain Details Per Protein
Protein Length Phospholipid/glycerol acyltransferase Tafazzin
UniProtKB:A0A8M3AV28 259
UniProtKB:F1QCP6 262
UniProtKB:A0A8M9PEW5 175
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations