Gene
phb
- ID
- ZDB-GENE-030131-6577
- Name
- prohibitin
- Symbol
- phb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to localize to mitochondrial inner membrane. Human ortholog(s) of this gene implicated in breast cancer and sporadic breast cancer. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; midbrain; and musculature system. Orthologous to human PHB (prohibitin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77919 (1 image)
- IMAGE:7161082 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| breast cancer | Alliance | {Breast cancer, susceptibility to} | 114480 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Band 7 domain | Band 7/SPFH domain superfamily | Prohibitin |
|---|---|---|---|---|
|
UniProtKB:A0A8M2BB12
|
309 | |||
|
UniProtKB:Q7T1D8
|
271 |
Interactions and Pathways
No data available
Plasmids
No data available