ZFIN is now using GRCz12tu for Genomic Data
Gene
phb
- ID
- ZDB-GENE-030131-6577
- Name
- prohibitin
- Symbol
- phb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; midbrain; and musculature system. Human ortholog(s) of this gene implicated in breast cancer and sporadic breast cancer. Orthologous to human PHB1 (prohibitin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77919 (1 image)
- IMAGE:7161082 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| breast cancer | Alliance | {Breast cancer, susceptibility to} | 114480 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Band 7 domain | Band 7/SPFH domain superfamily | Prohibitin |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BB12 | InterPro | 309 | |||
| UniProtKB:Q7T1D8 | InterPro | 271 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers