Gene

heatr1

ID
ZDB-GENE-030131-6378
Name
HEAT repeat containing 1
Symbol
heatr1 Nomenclature History
Previous Names
  • BAP28-like (1)
  • fi69e12
  • flj10359 (1)
  • wu:fi69e12
  • zgc:63510
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have snoRNA binding activity. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of apoptotic process; and regulation of RNA stability. Predicted to localize to 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Is expressed in eye; forebrain; immature eye; midbrain; and midbrain hindbrain boundary. Orthologous to human HEATR1 (HEAT repeat containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Azuma et al., 2006
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With heatr1 Human Ortholog
No data available
Associated With heatr1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR012954 BP28, C-terminal domain
Domain IPR022125 U3 small nucleolar RNA-associated protein 10, N-terminal
Family IPR040191 U3 small nucleolar RNA-associated protein 10
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold BP28, C-terminal domain U3 small nucleolar RNA-associated protein 10 U3 small nucleolar RNA-associated protein 10, N-terminal
UniProtKB:Q7SY48 2159
UniProtKB:A0A0R4IAU8 2159
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations