ZFIN is now using GRCz12tu for Genomic Data
Gene
nkx2.4a
- ID
- ZDB-GENE-030131-6336
- Name
- NK2 homeobox 4a
- Symbol
- nkx2.4a Nomenclature History
- Previous Names
-
- fi48a12
- wu:fi48a12 (1)
- zgc:171531
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within hypothalamus development. Predicted to be active in nucleus. Is expressed in caudal tuberculum; diencephalon; forebrain; hypothalamus; and intermediate hypothalamus. Orthologous to human NKX2-4 (NK2 homeobox 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox NK-like transcription regulators | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|
| UniProtKB:A8KB41 | InterPro | 345 | |||||
| UniProtKB:B3DG22 | InterPro | 336 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nkx2.4a-201
(1)
|
Ensembl | 1,684 nt | ||
| mRNA |
nkx2.4a-202
(1)
|
Ensembl | 1,350 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers