Gene
brf1b
- ID
- ZDB-GENE-030131-6248
- Name
- BRF1 RNA polymerase III transcription initiation factor subunit b
- Symbol
- brf1b Nomenclature History
- Previous Names
-
- fi40c10
- wu:fi40c10
- zgc:63497
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase III type 3 promoter sequence-specific DNA binding activity and transcription factor binding activity. Involved in cerebellum development and thrombocyte differentiation. Predicted to localize to transcription factor TFIIIB complex. Is expressed in head. Orthologous to human BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cerebellofaciodental syndrome | Alliance | Cerebellofaciodental syndrome | 616202 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR011665 | Brf1, TBP-binding domain |
| Domain | IPR013137 | Zinc finger, TFIIB-type |
| Domain | IPR013150 | Transcription factor TFIIB, cyclin-like domain |
| Domain | IPR013763 | Cyclin-like domain |
| Family | IPR000812 | Transcription factor TFIIB |
| Homologous_superfamily | IPR036915 | Cyclin-like superfamily |
Domain Details Per Protein
| Protein | Length | Brf1, TBP-binding domain | Cyclin-like domain | Cyclin-like superfamily | Transcription factor TFIIB | Transcription factor TFIIB, cyclin-like domain | Zinc finger, TFIIB-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6P9Z3
|
693 |
Interactions and Pathways
No data available
Plasmids
No data available