ZFIN is now using GRCz12tu for Genomic Data
Gene
tep1
- ID
- ZDB-GENE-030131-6153
- Name
- telomerase-associated protein 1
- Symbol
- tep1 Nomenclature History
- Previous Names
-
- si:ch211-284o19.1
- si:rp71-1g18.6
- wu:fb19f02
- wu:fi36h03 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA binding activity. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and stomach cancer. Orthologous to human TEP1 (telomerase associated protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150837 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR007111 | NACHT nucleoside triphosphatase |
| Domain | IPR008858 | TROVE domain |
| Domain | IPR025139 | Domain of unknown function DUF4062 |
| Domain | IPR041452 | APAF-1 helical domain |
| Domain | IPR045804 | Domain of unknown function DUF5920 |
| Family | IPR052652 | Telomerase Complex Component |
| Homologous_superfamily | IPR011047 | Quinoprotein alcohol dehydrogenase-like superfamily |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
| Homologous_superfamily | IPR037214 | TROVE domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | APAF-1 helical domain | Domain of unknown function DUF4062 | Domain of unknown function DUF5920 | NACHT nucleoside triphosphatase | P-loop containing nucleoside triphosphate hydrolase | Quinoprotein alcohol dehydrogenase-like superfamily | Telomerase Complex Component | TROVE domain | TROVE domain superfamily | von Willebrand factor A-like domain superfamily | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AXG0 | InterPro | 2677 | |||||||||||||
| UniProtKB:A0AB32TE43 | InterPro | 533 | |||||||||||||
| UniProtKB:A0AB32TH65 | InterPro | 532 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance