Gene

ldhd

ID

ZDB-GENE-030131-6140

Name

lactate dehydrogenase D

Symbol

ldhd Nomenclature History

Previous Names

wu:fi36b04
zgc:55447

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have D-lactate dehydrogenase (cytochrome) activity; D-lactate dehydrogenase activity; and flavin adenine dinucleotide binding activity. Involved in lactate catabolic process. Predicted to localize to mitochondrion. Orthologous to human LDHD (lactate dehydrogenase D).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55447 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Monroe et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ldhd Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		D-lactic aciduria with susceptibility to gout	245450

Associated With ldhd Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004113	FAD-binding oxidoreductase/transferase, type 4, C-terminal
Domain	IPR006094	FAD linked oxidase, N-terminal
Domain	IPR016166	FAD-binding domain, PCMH-type
Homologous_superfamily	IPR016164	FAD-linked oxidase-like, C-terminal
Homologous_superfamily	IPR016169	FAD-binding, type PCMH, subdomain 2
Homologous_superfamily	IPR016171	Vanillyl-alcohol oxidase, C-terminal subdomain 2
Homologous_superfamily	IPR036318	FAD-binding, type PCMH-like superfamily