Gene

cux1a

ID
ZDB-GENE-030131-5868
Name
cut-like homeobox 1a
Symbol
cux1a Nomenclature History
Previous Names
  • fi22b07
  • si:ch211-251d10.5
  • wu:fi22b07 (1)
  • wu:fk35a11
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in Golgi vesicle transport and negative regulation of transcription by RNA polymerase II. Predicted to localize to Golgi membrane and nucleus. Is expressed in brain. Orthologous to human CUX1 (cut like homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Oosterhof et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cux1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Global developmental delay with or without impaired intellectual development 618330
Associated With cux1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR003350 CUT domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length CUT domain Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Lambda repressor-like, DNA-binding domain superfamily
UniProtKB:A0A8M9QCL4 1424
UniProtKB:A0A8M2BJZ7 1480
UniProtKB:A0A8M9Q6L3 1439
UniProtKB:A0A2R8Q0A5 1466
UniProtKB:E7F4J9 1495
UniProtKB:A0A8M1RNM7 1451
UniProtKB:A0A2R8QFA5 1468
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA cux1a-202 (1) Havana 5997 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations