Gene

nploc4

ID

ZDB-GENE-030131-5658

Name

NPL4 homolog, ubiquitin recognition factor

Symbol

nploc4 Nomenclature History

Previous Names

npl4 (1)
wu:fi11f09
zgc:55988

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have ubiquitin binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to localize to nucleus. Orthologous to human NPLOC4 (NPL4 homolog, ubiquitin recognition factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7140486 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nploc4 Human Ortholog

No data available

Associated With nploc4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001876	Zinc finger, RanBP2-type
Domain	IPR007716	NPL4, zinc-binding putative
Domain	IPR007717	Nuclear pore localisation protein NPL4, C-terminal
Domain	IPR024682	Nuclear pore localisation protein Npl4, ubiquitin-like domain
Domain	IPR037518	MPN domain
Family	IPR016563	Nuclear protein localization protein 4
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR036443	Zinc finger, RanBP2-type superfamily