Gene
kpna4
- ID
- ZDB-GENE-030131-5584
- Name
- karyopherin alpha 4 (importin alpha 3)
- Symbol
- kpna4 Nomenclature History
- Previous Names
-
- wu:fa56d07
- wu:fa66g10
- wu:fe14c04
- wu:fi04h11
- wu:fi19b05
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to localize to cytosol; nuclear pore; and nucleoplasm. Orthologous to human KPNA4 (karyopherin subunit alpha 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55488 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ping et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002652 | Importin-alpha, importin-beta-binding domain |
| Family | IPR024931 | Importin subunit alpha |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR036975 | Importin-alpha, importin-beta-binding domain superfamily |
| Repeat | IPR000225 | Armadillo |
| Repeat | IPR032413 | Atypical Arm repeat |
Domain Details Per Protein
| Protein | Length | Armadillo | Armadillo-like helical | Armadillo-type fold | Atypical Arm repeat | Importin-alpha, importin-beta-binding domain | Importin-alpha, importin-beta-binding domain superfamily | Importin subunit alpha |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVY9
|
521 |
Interactions and Pathways
No data available
Plasmids
No data available