Gene

nhp2

ID
ZDB-GENE-030131-533
Name
NHP2 ribonucleoprotein homolog (yeast)
Symbol
nhp2 Nomenclature History
Previous Names
  • nola2
  • wu:fb36b10
  • wu:fd61a03
  • zgc:73227
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have box H/ACA snoRNA binding activity. Predicted to be involved in nucleic acid metabolic process. Predicted to localize to box H/ACA snoRNP complex and telomerase holoenzyme complex. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 2. Is expressed in several structures, including digestive system; immature eye; midbrain; retina; and segmental plate. Orthologous to human NHP2 (NHP2 ribonucleoprotein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nhp2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive dyskeratosis congenita 2 Alliance Dyskeratosis congenita, autosomal recessive 2 613987
Associated With nhp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004038 Ribosomal protein eL8/eL30/eS12/Gadd45
Family IPR002415 H/ACA ribonucleoprotein complex, subunit Nhp2-like
Family IPR018492 Ribosomal protein eL8/Nhp2 family
Homologous_superfamily IPR029064 Ribosomal protein eL30-like superfamily
Domain Details Per Protein
Protein Length H/ACA ribonucleoprotein complex, subunit Nhp2-like Ribosomal protein eL30-like superfamily Ribosomal protein eL8/eL30/eS12/Gadd45 Ribosomal protein eL8/Nhp2 family
UniProtKB:Q6PBV6 150
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations