Gene
slc25a4
- ID
- ZDB-GENE-030131-5275
- Name
- solute carrier family 25 member 4
- Symbol
- slc25a4 Nomenclature History
- Previous Names
-
- fa22e07
- wu:fa22e07
- zgc:77591
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have ATP:ADP antiporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to integral component of membrane and mitochondrial inner membrane. Is expressed in cephalic musculature; hypaxial myotome region; musculature system; myotome; and somite. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77591 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 | Alliance | Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 2 | 609283 |
mitochondrial DNA depletion syndrome 12a | Alliance | Mitochondrial DNA depletion syndrome 12A (cardiomyopathic type) AD | 617184 |
mitochondrial DNA depletion syndrome 12b | Alliance | Mitochondrial DNA depletion syndrome 12B (cardiomyopathic type) AR | 615418 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | ADP/ATP carrier protein, eukaryotic type | Mitochondrial carrier domain superfamily | Mitochondrial carrier protein | Mitochondrial substrate/solute carrier |
---|---|---|---|---|---|
UniProtKB:Q6NX10
|
298 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
slc25a4-201
(1)
|
1434 nt |
Interactions and Pathways
No data available
Plasmids
No data available