Gene

rnh1

ID
ZDB-GENE-030131-4718
Name
ribonuclease/angiogenin inhibitor 1
Symbol
rnh1 Nomenclature History
Previous Names
  • im:7039360
  • si:ch211-213a13.3
  • wu:fd55g05
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome (multiple); and urticaria. Orthologous to several human genes including NLRP12 (NLR family pyrin domain containing 12); NLRP13 (NLR family pyrin domain containing 13); and NLRP14 (NLR family pyrin domain containing 14).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
No data available
Human Disease
Associated With rnh1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Encephalopathy, acute, infection-induced, susceptibility to, 12} 620461
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Associated With rnh1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007111 NACHT nucleoside triphosphatase
Domain IPR029495 NACHT-associated domain
Domain IPR041075 NOD1/2, winged helix domain
Domain IPR041267 NACHT, LRR and PYD domains-containing protein, helical domain HD2
Family IPR051261 NOD-like receptor
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Domain Details Per Protein
Protein Additional Resources Length Leucine-rich repeat Leucine-rich repeat, cysteine-containing subtype Leucine-rich repeat domain superfamily NACHT-associated domain NACHT, LRR and PYD domains-containing protein, helical domain HD2 NACHT nucleoside triphosphatase NOD1/2, winged helix domain NOD-like receptor P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0AB32T9V1 InterPro 2440
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 22
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:ch211-213a13.2-202 (1)
Ensembl
Ensembl 2,671 nt
ZFIN BLAST
mRNA si:ch211-213a13.2-203 (1)
Ensembl
Ensembl 1,998 nt
ZFIN BLAST
mRNA si:ch211-213a13.2-205 (1)
Ensembl
Ensembl 1,998 nt
ZFIN BLAST
mRNA si:ch211-213a13.2-206 (1)
Ensembl
Ensembl 1,717 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-213A13ZFIN Curated Data
EncodesESTIMAGE:7039360
Has ArtifactESTfd55g05
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_068216559 (1)7686 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX248395 (2)206668 nt
MegaBLAST
PolypeptideUniProtKB:A0AB32T9V1 (1)2440 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRNH111
Amino acid sequence comparison (1)
Citations
TSV
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