Gene
chd4b
- ID
- ZDB-GENE-030131-4532
- Name
- chromodomain helicase DNA binding protein 4b
- Symbol
- chd4b Nomenclature History
- Previous Names
-
- si:ch211-57k11.10
- wu:fb44b12
- wu:fd12d03 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and metal ion binding activity. Predicted to localize to nucleus. Is expressed in blastomere and central nervous system. Orthologous to human CHD4 (chromodomain helicase DNA binding protein 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Sifrim-Hitz-Weiss syndrome | Alliance | Sifrim-Hitz-Weiss syndrome | 617159 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR002464 | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site |
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR000330 | SNF2, N-terminal |
| Domain | IPR000953 | Chromo/chromo shadow domain |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR009462 | CHD subfamily II, SANT-like domain |
| Domain | IPR009463 | Domain of unknown function DUF1087 |
| Domain | IPR012957 | CHD, C-terminal 2 |
| Domain | IPR012958 | CHD, N-terminal |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR023780 | Chromo domain |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR016197 | Chromo-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR038718 | SNF2-like, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CHD, C-terminal 2 | CHD, N-terminal | CHD subfamily II, SANT-like domain | Chromo/chromo shadow domain | Chromo domain | Chromo-like domain superfamily | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site | Domain of unknown function DUF1087 | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PC64
|
1948 | ||||||||||||||||||
|
UniProtKB:A0A8M9PNR4
|
1890 | ||||||||||||||||||
|
UniProtKB:A0A8M9PDP3
|
1949 | ||||||||||||||||||
|
UniProtKB:A0A8N7T760
|
1952 | ||||||||||||||||||
|
UniProtKB:F1RBT2
|
1953 | ||||||||||||||||||
|
UniProtKB:A0A8M9PN35
|
1891 |
Interactions and Pathways
No data available
Plasmids
No data available