Gene

anln

ID
ZDB-GENE-030131-4486
Name
anillin, actin binding protein
Symbol
anln Nomenclature History
Previous Names
  • si:ch211-197n10.2
  • wu:fb74d05 (1)
  • wu:fd10d09
  • wu:fi41f04 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have GTP-Rho binding activity. Involved in asymmetric cell division; glomerular filtration; and glomerulus development. Predicted to localize to actomyosin contractile ring. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Is expressed in brain; optic cup; optic tectum; and retina. Orthologous to human ANLN (anillin actin binding protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With anln Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
focal segmental glomerulosclerosis 8 Alliance Focal segmental glomerulosclerosis 8 616032
Associated With anln Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR012966 Anillin homology domain
Domain IPR031970 Anillin, N-terminal domain
Domain IPR037840 Anillin, PH domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Anillin homology domain Anillin, N-terminal domain Anillin, PH domain PH-like domain superfamily Pleckstrin homology domain
UniProtKB:Q1LUB2 1089
UniProtKB:A0A286Y917 1171
UniProtKB:F6NI04 158
UniProtKB:F1QJH8 1153
UniProtKB:A4IFW5 1153
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations