Gene
ywhabl
- ID
- ZDB-GENE-030131-448
- Name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
- Symbol
- ywhabl Nomenclature History
- Previous Names
-
- hm:zehn0976
- iota2 (1)
- wu:fb33b01
- zehn0976
- zgc:77351
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to be involved in intracellular protein localization and signal transduction. Predicted to be active in cytoplasm. Is expressed in head; nervous system; otic vesicle; post-vent region; and tail bud. Orthologous to human YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73065 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa6430 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | 14-3-3 domain | 14-3-3 domain superfamily | 14-3-3 protein | 14-3-3 protein, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:Q6PC82 | InterPro | 245 | ||||
| UniProtKB:Q6P102 | InterPro | 245 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ywhabl-201
(1)
|
Ensembl | 1,882 nt | ||
| mRNA |
ywhabl-202
(1)
|
Ensembl | 1,742 nt | ||
| mRNA |
ywhabl-203
(1)
|
Ensembl | 1,797 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-56F14 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-79D12 | ZFIN Curated Data | |
| Encodes | EST | fb33b01 | ||
| Encodes | EST | zehn0976 | ||
| Encodes | cDNA | MGC:73065 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:77351 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_199562 (1) | 1764 nt | ||
| Genomic | GenBank:BX005256 (1) | 199468 nt | ||
| Polypeptide | UniProtKB:Q6P102 (1) | 245 aa |
No data available
- Biswas, S., Chawda, M., Gudi, R., Bellare, J. (2023) Neuroprotective effects of nanogold-based Ayurveda medicine Suvarna Bhasma against rotenone-induced Parkinson's-like model. Journal of Ayurveda and integrative medicine. 15:100854100854
- Cao, J., Tan, X. (2018) Comparative and evolutionary analysis of the 14-3-3 family genes in eleven fishes. Gene. 662:76-82
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Wu, C.C., Kruse, F., Vasudevarao, M.D., Junker, J.P., Zebrowski, D.C., Fischer, K., Noël, E.S., Grün, D., Berezikov, E., Engel, F.B., van Oudenaarden, A., Weidinger, G., Bakkers, J. (2016) Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Developmental Cell. 36(1):36-49
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Zhao, S., Xie, P., Li, G., Jun, C., Cai, Y., Xiong, Q., and Zhao, Y. (2012) The proteomic study on cellular responses of the testes of zebrafish (Danio rerio) exposed to microcystin-RR. Proteomics. 12(2):300-312
- Zhuo, H.Q., Huang, L., Huang, H.Q., and Cai, Z. (2012) Effects of chronic tramadol exposure on the zebrafish brain: A proteomic study. Journal of proteomics. 75(11):3351-3364
- Besser, J., Bagowski, C.P., Salas-Vidal, E., van Hemert, M.J., Bussmann, J., and Spaink, H.P. (2007) Expression analysis of the family of 14-3-3 proteins in zebrafish development. Gene expression patterns : GEP. 7(4):511-520
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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