Gene
zbtb48
- ID
- ZDB-GENE-030131-4450
- Name
- zinc finger and BTB domain containing 48
- Symbol
- zbtb48 Nomenclature History
- Previous Names
-
- fd07a08
- wu:fd07a08
- wu:fe16d08
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in chromosome. Orthologous to human ZBTB48 (zinc finger and BTB domain containing 48).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la014372Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| mz144 | Allele with one deletion | Unknown | Unknown | not specified |
1 - 2 of 2
Show
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-zbtb48 | Goh et al., 2025 | |
| CRISPR2-zbtb48 | Goh et al., 2025 |
1 - 2 of 2
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Snail/Krueppel C2H2-type Zinc-finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|---|
| UniProtKB:E7FDZ5 | InterPro | 760 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zbtb48-201
(1)
|
Ensembl | 845 nt | ||
| mRNA |
zbtb48-202
(1)
|
Ensembl | 2,572 nt | ||
| mRNA |
zbtb48-203
(1)
|
Ensembl | 1,470 nt |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_691074 (1) | 3443 nt | ||
| Genomic | GenBank:CR376748 (1) | 233351 nt | ||
| Polypeptide | UniProtKB:E7FDZ5 (1) | 760 aa |
- Goh, S.Y.C., Fradera-Sola, A., Wittkopp, N., Şerifoğlu, N., Godinho Ferreira, M., Ketting, R.F., Butter, F. (2025) Zbtb48 is a regulator of Mtfp1 expression in zebrafish. Communications biology. 8:277277
- Zebrafish Nomenclature Committee (2024) Nomenclature Data Curation (2024). Nomenclature Committee Submission.
- Kuretani, A., Yamamoto, T., Taira, M., Michiue, T. (2021) Evolution of hes gene family in vertebrates: the hes5 cluster genes have specifically increased in frogs. BMC ecology and evolution. 21:147
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Steinke, D., Salzburger, W., Braasch, I., and Meyer, A. (2006) Many genes in fish have species-specific asymmetric rates of molecular evolution. BMC Genomics. 7(1):20
1 - 7 of 7
Show