Gene
mt2
- ID
- ZDB-GENE-030131-4174
- Name
- metallothionein 2
- Symbol
- mt2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Involved in several processes, including positive regulation of cell migration involved in sprouting angiogenesis; positive regulation of vascular endothelial growth factor production; and response to copper ion. Human ortholog(s) of this gene implicated in carotid stenosis and type 2 diabetes mellitus. Is expressed in several structures, including digestive system; nervous system; pleuroperitoneal region; vein; and yolk. Orthologous to human MT2A (metallothionein 2A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 30 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Schuermann et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Metallothionein domain superfamily | Metallothionein domain superfamily, vertebrate | Metallothionein, vertebrate | Metallothionein, vertebrate, metal binding site |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZSY6
|
60 | ||||
|
UniProtKB:Q1LV07
|
60 | ||||
|
UniProtKB:P52722
|
60 |
Interactions and Pathways
No data available
Plasmids
No data available