Gene

usp16

ID

ZDB-GENE-030131-4153

Name

ubiquitin specific peptidase 16

Symbol

usp16 Nomenclature History

Previous Names

wu:fc76b02
wu:fc76b08

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have several functions, including cysteine-type peptidase activity; transcription coactivator activity; and zinc ion binding activity. Predicted to be involved in several processes, including histone H2A K63-linked deubiquitination; positive regulation of gene expression; and protein homotetramerization. Predicted to localize to nucleus. Orthologous to human USP16 (ubiquitin specific peptidase 16).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7160401 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With usp16 Human Ortholog

No data available

Associated With usp16 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018200	Ubiquitin specific protease, conserved site
Domain	IPR001394	Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain	IPR001607	Zinc finger, UBP-type
Domain	IPR028889	Ubiquitin specific protease domain
Family	IPR030849	Ubiquitin carboxyl-terminal hydrolase 16
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily

Domain Details Per Protein

Protein	Length	Papain-like cysteine peptidase superfamily	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 16	Ubiquitin specific protease, conserved site	Ubiquitin specific protease domain	Zinc finger, RING/FYVE/PHD-type	Zinc finger, UBP-type
UniProtKB:A8HAL1 InterPro
UniProtKB:A0A8M3AQ52 InterPro	814
UniProtKB:A0A8M9QHB9 InterPro	741
UniProtKB:A0A8M9QC36 InterPro	815

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	usp16-201 (1) Ensembl	Havana	3660 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	usp16-202 (1) Ensembl	Havana	746 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	usp16-203 (1) Ensembl	Havana	488 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations