Gene

hltf

ID
ZDB-GENE-030131-3306
Name
helicase-like transcription factor
Symbol
hltf Nomenclature History
Previous Names
  • smarca3 (1)
  • wu:fc33f07
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable ATP-dependent activity, acting on DNA. Predicted to be involved in DNA repair. Predicted to be active in nucleus. Is expressed in head and post-vent region. Orthologous to human HLTF (helicase like transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Li et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
kh18Allele with one deletionExon 8FrameshiftCRISPR
sa12894Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-hltfShin et al., 2021
MO1-hltfN/AHuang et al., 2013
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Human Disease
Associated With hltf Human Ortholog
No data available
Associated With hltf Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR000330 SNF2, N-terminal
Domain IPR001650 Helicase, C-terminal domain-like
Domain IPR001841 Zinc finger, RING-type
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
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Domain Details Per Protein
Protein Additional Resources Length Helicase, C-terminal domain-like Helicase superfamily 1/2, ATP-binding domain HIRAN domain P-loop containing nucleoside triphosphate hydrolase SNF2-like, N-terminal domain superfamily SNF2, N-terminal SNF2/RAD54 Helicase and Transcription Factor SNF2/RAD5-like, C-terminal helicase domain Zinc finger, C3HC4 RING-type Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site
UniProtKB:A0A8M9P9A8 InterPro 907
UniProtKB:A0A8M3APR6 InterPro 491
UniProtKB:A0A2R8Q5J1 InterPro 908
UniProtKB:A0A8M3AXA6 InterPro 941
UniProtKB:A0A8M2BAK6 InterPro 942
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 2
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hltf-201 (1) Ensembl 3,062 nt
mRNA hltf-205 (1) Ensembl 3,721 nt
ncRNA hltf-002 (1) Ensembl 719 nt
ncRNA hltf-003 (1) Ensembl 638 nt
ncRNA hltf-004 (1) Ensembl 741 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-4M11ZFIN Curated Data
EncodesESTfc33f07
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHLTF3
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseHltf3
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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