Gene
taldo1
- ID
- ZDB-GENE-030131-3277
- Name
- transaldolase 1
- Symbol
- taldo1 Nomenclature History
- Previous Names
-
- wu:fc32g02
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable transaldolase activity. Predicted to be involved in pentose-phosphate shunt, non-oxidative branch. Predicted to act upstream of or within carbohydrate metabolic process and pentose-phosphate shunt. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder. Orthologous to human TALDO1 (transaldolase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Lam et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Targeting Reagent | Created Alleles | Citations |
---|---|---|
CRISPR1-taldo1 | (2) | |
CRISPR2-taldo1 | (2) | |
CRISPR3-taldo1 | (2) | |
CRISPR4-taldo1 | (2) | |
CRISPR5-taldo1 | (2) | |
CRISPR6-taldo1 | (2) | |
CRISPR7-taldo1 | (2) | |
CRISPR8-taldo1 | (2) |
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Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Transaldolase deficiency | 606003 |
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Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Aldolase-type TIM barrel | Transaldolase, active site | Transaldolase/Fructose-6-phosphate aldolase | Transaldolase type 1 |
---|---|---|---|---|---|---|
UniProtKB:Q6P6Y0 | InterPro | 337 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
taldo1-201
(1)
|
Ensembl | 926 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_199687 (1) | 3348 nt | ||
Genomic | GenBank:CABZ01118896 (1) | 21284 nt | ||
Polypeptide | UniProtKB:Q6P6Y0 (1) | 337 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Nguyen, V.T., Fuse, Y., Tamaoki, J., Akiyama, S.I., Muratani, M., Tamaru, Y., Kobayashi, M. (2016) Conservation of the Nrf2-Mediated Gene Regulation of Proteasome Subunits and Glucose Metabolism in Zebrafish. Oxidative medicine and cellular longevity. 2016:5720574
- Bui-Nguyen, T.M., Baer, C.E., Lewis, J.A., Yang, D., Lein, P.J., Jackson, D.A. (2015) Dichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio. BMC Genomics. 16:853
- Chatzopoulou, A., Roy, U., Meijer, A.H., Alia, A., Spaink, H.P., Schaaf, M.J. (2015) Transcriptional and Metabolic Effects of Glucocorticoid Receptor α and β Signaling in Zebrafish. Endocrinology. 156(5):1757-69
- Moreno-Mateos, M.A., Vejnar, C.E., Beaudoin, J.D., Fernandez, J.P., Mis, E.K., Khokha, M.K., Giraldez, A.J. (2015) CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo. Nature Methods. 12:982-8
- Kolmakov, N.N., Kube, M., Reinhardt, R., and Canario, A.V. (2008) Analysis of the goldfish Carassius auratus olfactory epithelium transcriptome reveals the presence of numerous non-olfactory GPCR and putative receptors for progestin pheromones. BMC Genomics. 9:429
- Lam, S.H., Winata, C.L., Tong, Y., Korzh, S., Lim, W.S., Korzh, V., Spitsbergen, J., Mathavan, S., Miller, L.D., Liu, E.T., and Gong, Z. (2006) Transcriptome Kinetics of Arsenic-induced Adaptive Response in Zebrafish Liver. Physiological Genomics. 27(3):351-361
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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