ZFIN is now using GRCz12tu for Genomic Data
Gene
nampt2
- ID
- ZDB-GENE-030131-2931
- Name
- nicotinamide phosphoribosyltransferase 2
- Symbol
- nampt2 Nomenclature History
- Previous Names
-
- namptb (1)
- im:7051384
- wu:fc21g12
- wu:fc27h03
- wu:fd15d03
- zgc:55764
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable nicotinamide phosphoribosyltransferase activity. Predicted to be involved in NAD biosynthetic process. Predicted to act upstream of or within pyridine nucleotide biosynthetic process and rhythmic process. Predicted to be located in cytoplasm; extracellular space; and nucleus. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase).
- Genome Resources
- Note
-
This gene name was updated because the phylogenetic tree indicates this was the result of a duplication event PRIOR to the divergence of ray- and lobe-fin fishes and not the teleost WGD
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55764 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR041525 | Nicotinate/nicotinamide phosphoribosyltransferase |
| Domain | IPR041529 | Nicotinamide phosphoribosyltransferase, N-terminal domain |
| Family | IPR016471 | Nicotinamide phosphoribosyl transferase |
| Homologous_superfamily | IPR013785 | Aldolase-type TIM barrel |
| Homologous_superfamily | IPR036068 | Nicotinate phosphoribosyltransferase-like, C-terminal |
Domain Details Per Protein
| Protein | Additional Resources | Length | Aldolase-type TIM barrel | Nicotinamide phosphoribosyl transferase | Nicotinamide phosphoribosyltransferase, N-terminal domain | Nicotinate/nicotinamide phosphoribosyltransferase | Nicotinate phosphoribosyltransferase-like, C-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:F1RDZ8 | InterPro | 498 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
namptb-201
(1)
|
Ensembl | 2,020 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers