ZFIN is now using GRCz12tu for Genomic Data
Gene
bcar1
- ID
- ZDB-GENE-030131-2774
- Name
- BCAR1 scaffold protein, Cas family member
- Symbol
- bcar1 Nomenclature History
- Previous Names
-
- fc17f11
- wu:fc17f11 (1)
- zgc:175192
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within regulation of lymphangiogenesis and regulation of sprouting angiogenesis. Predicted to be located in anchoring junction. Predicted to be active in cytoplasm and focal adhesion. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in breast ductal carcinoma. Orthologous to human BCAR1 (BCAR1 scaffold protein, Cas family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from O'Hare et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Wisniewski et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR014928 | Serine rich protein interaction domain |
| Domain | IPR021901 | CAS family, C-terminal |
| Domain | IPR035745 | BCAR1, SH3 domain |
| Family | IPR037362 | CAS family |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR038319 | CAS, serine rich four helix bundle domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | BCAR1, SH3 domain | CAS family | CAS family, C-terminal | CAS, serine rich four helix bundle domain superfamily | Serine rich protein interaction domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8QJQ5 | InterPro | 919 | |||||||
| UniProtKB:A0A2R8Q9D0 | InterPro | 946 | |||||||
| UniProtKB:A0A8M9PM80 | InterPro | 961 | |||||||
| UniProtKB:B5DE36 | InterPro | 919 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers