Gene

pik3r5

ID
ZDB-GENE-030131-2308
Name
phosphoinositide-3-kinase, regulatory subunit 5
Symbol
pik3r5 Nomenclature History
Previous Names
  • fc03h05
  • si:ch73-203d16.1
  • wu:fc03h05 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in G protein-coupled receptor signaling pathway and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Predicted to be part of phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in ataxia with oculomotor apraxia type 3 and colon cancer. Orthologous to human PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pik3r5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
ataxia with oculomotor apraxia type 3 Alliance Ataxia-oculomotor apraxia 3 615217
1 - 1 of 1
Associated With pik3r5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019522 Phosphoinositide 3-kinase regulatory subunit 5/6
1 - 1 of 1
Domain Details Per Protein
Protein Additional Resources Length Phosphoinositide 3-kinase regulatory subunit 5/6
UniProtKB:A0A8M3BAC9 InterPro 865
UniProtKB:A0A8M9Q7E2 InterPro 874
UniProtKB:A0A0R4IPI8 InterPro 865
UniProtKB:A0AB32TLL8 InterPro 872
UniProtKB:A0AB32TW45 InterPro 872
1 - 5 of 5
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pik3r5-201 (1) Ensembl 2,823 nt
mRNA pik3r5-202 (1) Ensembl 4,659 nt
mRNA pik3r5-203 (1) Ensembl 4,591 nt
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations