Gene
sin3ab
- ID
- ZDB-GENE-030131-2066
- Name
- SIN3 transcription regulator family member Ab
- Symbol
- sin3ab Nomenclature History
- Previous Names
-
- fb95g11
- wu:fb95g11
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to contribute to histone deacetylase activity. Predicted to be involved in histone deacetylation and negative regulation of transcription by RNA polymerase II. Predicted to localize to Sin3 complex. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from DeMoya et al., 2023
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| chromosome 15q24 deletion syndrome | Alliance | Witteveen-Kolk syndrome | 613406 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Histone deacetylase interacting domain | Paired amphipathic helix | Paired amphipathic helix superfamily | Sin3, C-terminal | Transcriptional regulatory protein Sin3-like |
|---|---|---|---|---|---|---|
|
UniProtKB:E7F0R9
|
1262 | |||||
|
UniProtKB:A0A8M3B4C3
|
1269 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
sin3ab-201
(1)
|
Havana | 5330 nt | |
| mRNA |
sin3ab-202
(1)
|
Havana | 1598 nt | |
| ncRNA |
sin3ab-002
(1)
|
Havana | 687 nt |
Interactions and Pathways
No data available
Plasmids
No data available