Gene
clcn6
- ID
- ZDB-GENE-030131-2056
- Name
- chloride channel 6
- Symbol
- clcn6 Nomenclature History
- Previous Names
-
- wu:fb95f01
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have chloride transmembrane transporter activity. Predicted to be involved in chloride transport and transmembrane transport. Predicted to localize to intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in coronary artery disease. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Orthologous to human CLCN6 (chloride voltage-gated channel 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodegeneration, childhood-onset, hypotonia, respiratory insufficiency and brain imaging abnormalities | 619173 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CBS domain | CBS domain superfamily | Chloride channel ClC-6 | Chloride channel, core | Chloride channel, voltage gated |
|---|---|---|---|---|---|---|
|
UniProtKB:E7F798
|
863 |
Interactions and Pathways
No data available
Plasmids
No data available