Gene
gas8
- ID
- ZDB-GENE-030131-1980
- Name
- growth arrest-specific 8
- Symbol
- gas8 Nomenclature History
- Previous Names
-
- wu:fb93e12
- zgc:66271
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have Rab GTPase binding activity. Involved in muscle cell development; otolith development; and positive regulation of smoothened signaling pathway. Predicted to localize to Golgi apparatus; ciliary basal body; and microtubule. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Is expressed in neural tube; otic placode; otic vesicle; and pronephric duct. Orthologous to human GAS8 (growth arrest specific 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66271 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 33 | Alliance | Ciliary dyskinesia, primary, 33 | 616726 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Growth arrest-specific protein 8 | Growth arrest-specific protein 8 domain |
|---|---|---|---|
|
UniProtKB:F1QNW4
|
475 |
Interactions and Pathways
No data available
Plasmids
No data available