kat7b

ID

ZDB-GENE-030131-1901

Name

K(lysine) acetyltransferase 7b

Symbol

kat7b Nomenclature History

Previous Names

kat7
fi16d05
MYST-HAT2 (1)
myst2
wu:fb92a01 (1)
wu:fi16d05 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable chromatin binding activity; histone acetyltransferase activity; and transcription coregulator activity. Acts upstream of or within blood vessel development. Predicted to be part of histone H3-K14 acetyltransferase complex. Predicted to be active in chromatin and nucleus. Is expressed in telencephalon. Orthologous to human KAT7 (lysine acetyltransferase 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55348 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Yan et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kat7b Human Ortholog

No data available

Associated With kat7b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002717	Histone acetyltransferase domain, MYST-type
Domain	IPR040706	MYST, zinc finger domain
Family	IPR050603	MYST family histone acetyltransferases
Homologous_superfamily	IPR016181	Acyl-CoA N-acyltransferase
Homologous_superfamily	IPR036060	Zinc finger, C2H2C-type superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Repeat	IPR002515	Zinc finger, C2H2C-type