ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
otop1
- ID
- ZDB-GENE-030131-1613
- Name
- otopetrin 1
- Symbol
- otop1 Nomenclature History
- Previous Names
- 
    
        
    
    
        
        - backstroke
- bks
- wu:fb76b02 (1)
- zgc:103626
 
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables cholesterol binding activity; identical protein binding activity; and proton channel activity. Involved in proton transmembrane transport. Acts upstream of or within otolith formation and otolith mineralization. Is active in membrane. Is expressed in lateral line system; otic vesicle; vestibuloauditory system; and yolk syncytial layer. Orthologous to human OTOP1 (otopetrin 1).
- Genome Resources
- 
    
        
    
    
        
        - Alliance (1)
- Gene:322893 (1)
 
- Note
- None
- Comparative Information
- 
    
        
        
              
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- 
    
        
    
    
        
        - MGC:103626 (14 images)
 
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Type | InterPro ID | Name | 
|---|---|---|
| Family | IPR004878 | Otopetrin | 
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | Otopetrin | 
|---|---|---|---|
| UniProtKB:Q7ZWK8 | InterPro | 586 | 
- Genome Browsers
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers
- Comparative Orthology
- Alliance
