Gene

lpar5a

ID
ZDB-GENE-030131-1193
Name
lysophosphatidic acid receptor 5a
Symbol
lpar5a Nomenclature History
Previous Names
  • lpar6
  • lpar6l (1)
  • p2ry5
  • wu:fb62d01
  • zgc:66034
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor activity. Predicted to be involved in behavioral response to pain and positive regulation of CREB transcription factor activity. Predicted to localize to integral component of membrane. Orthologous to human LPAR5 (lysophosphatidic acid receptor 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lpar5a Human Ortholog
No data available
Associated With lpar5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:Q6PHE1 328
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA lpar5a-201 (1) Havana 1571 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Woods et al. (2005, ZDB-PUB-050823-6) reported orthology to P2RY5 (LPAR6) based on sequence similarity. Subsequent curator analysis showed that the zgc:153784 protein has much higher identity to LPAR6. Based on this analysis, the orthology reported by Woods, et al has been removed. Orthology from Auer et al. 2007 (ZDB-PUB-070513-23), where the zebrafish ortholog may have been misidentified, has also been removed.
Citations