Gene

suclg2

ID

ZDB-GENE-030114-3

Name

succinate-CoA ligase GDP-forming subunit beta

Symbol

suclg2 Nomenclature History

Previous Names

SUCLGb (1)
cb625 (1)
fd44e06
wu:fd44e06

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in succinyl-CoA metabolic process and tricarboxylic acid cycle. Predicted to localize to mitochondrion and succinate-CoA ligase complex. Is expressed in lens; liver; pronephric duct; solid lens vesicle; and yolk syncytial layer. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb625 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With suclg2 Human Ortholog

No data available

Associated With suclg2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017866	Succinyl-CoA synthetase, beta subunit, conserved site
Domain	IPR005811	ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain
Domain	IPR013650	ATP-grasp fold, succinyl-CoA synthetase-type
Family	IPR005809	Succinate--CoA ligase-like, beta subunit
Family	IPR034722	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
Homologous_superfamily	IPR013815	ATP-grasp fold, subdomain 1
Homologous_superfamily	IPR016102	Succinyl-CoA synthetase-like