Gene

lmo1

ID
ZDB-GENE-021115-6
Name
LIM domain only 1
Symbol
lmo1 Nomenclature History
Previous Names
  • lmo1b
  • cb524 (1)
  • etID41074.7 (1)
  • wu:fb76g02 (1)
  • zgc:109794
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anterior axial hypoblast; brain; neural tube; pancreas primordium; and presumptive diencephalon. Orthologous to human LMO1 (LIM domain only 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
zdf51Allele with multiple variantsUnknownUnknownTALEN
zdf52Allele with one delinsUnknownUnknownCRISPR
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Sequence Targeting Reagents
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Human Disease
Associated With lmo1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leukemia, T-cell acute lymphoblastic 186921
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Associated With lmo1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001781 Zinc finger, LIM-type
Family IPR050945 LMO/RBTN Transcription Factors
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Domain Details Per Protein
Protein Additional Resources Length LMO/RBTN Transcription Factors Zinc finger, LIM-type
UniProtKB:A0A8M9Q7H5 InterPro 159
UniProtKB:A0A0R4IIA9 InterPro 175
UniProtKB:B2GQX2 InterPro 155
UniProtKB:A0A8M9Q161 InterPro 179
UniProtKB:Q8JFQ2 InterPro 155
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 7
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lmo1-201 (1) Ensembl 1,761 nt
mRNA lmo1-202 (1) Ensembl 809 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(lmo1-E1B:EGFP)
  • Danio rerio
4 (2)
Tg(Tru.Lck:lmo1)
    • lmo1
    • Danio rerio
    • Takifugu rubripes
    1 (2)
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    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACCH73-226L19ZFIN Curated Data
    Contained inBACDKEY-61M24
    EncodesESTcb524Thisse et al., 2001
    EncodesESTfb76g02ZFIN Curated Data
    EncodescDNAMGC:109794ZFIN Curated Data
    EncodescDNAMGC:192080ZFIN Curated Data
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanLMO111
    Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    MouseLmo17
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations
    1 - 10 of 18
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