ZFIN is now using GRCz12tu for Genomic Data
Gene
trpm7
- ID
- ZDB-GENE-021115-2
- Name
- transient receptor potential cation channel, subfamily M, member 7
- Symbol
- trpm7 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium channel activity and protein kinase activity. Predicted to be involved in calcium ion transport and monoatomic cation transmembrane transport. Predicted to be active in plasma membrane. Is expressed in several structures, including digestive system; immature eye; integument; nervous system; and renal system. Used to study sinoatrial node disease. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1. Orthologous to human TRPM7 (transient receptor potential cation channel subfamily M member 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 58 figures from 33 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb495 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- 34 figures from 11 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 | Alliance | {Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to} | 105500 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| sinoatrial node disease | WT + MO3-trpm7 | standard conditions | Sah et al., 2013 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004166 | Alpha-type protein kinase, alpha-kinase domain |
| Domain | IPR005821 | Ion transport domain |
| Domain | IPR029601 | Transient receptor potential cation channel subfamily M member 7, alpha-kinase domain |
| Domain | IPR032415 | TRPM, tetramerisation domain |
| Domain | IPR041491 | TRPM, SLOG domain |
| Domain | IPR057366 | TRPM-like domain |
| Family | IPR050927 | Transient receptor potential cation channel M |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR037162 | TRPM, tetramerisation domain superfamily |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers