ZFIN is now using GRCz12tu for Genomic Data
Gene
gstp1.2
- ID
- ZDB-GENE-020806-4
- Name
- glutathione S-transferase pi 1.2
- Symbol
- gstp1.2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables glutathione transferase activity. Acts upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in mitochondrion and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including digestive system; endoderm; pleuroperitoneal region; sensory system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); carcinoma (multiple); hematologic cancer (multiple); reproductive organ cancer (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (glutathione S-transferase pi 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 61 figures from 39 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb356 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Zhang et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004045 | Glutathione S-transferase, N-terminal |
| Domain | IPR004046 | Glutathione S-transferase, C-terminal |
| Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
| Family | IPR003082 | Glutathione S-transferase, Pi class |
| Family | IPR040079 | Glutathione transferase family |
| Family | IPR050213 | Glutathione S-transferase superfamily |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
| Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Glutathione S-transferase, C-terminal | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione S-transferase, N-terminal | Glutathione S-transferase, Pi class | Glutathione S-transferase superfamily | Glutathione transferase family | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9DDU5 | InterPro | 208 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers