Gene

vps18

ID
ZDB-GENE-020419-33
Name
VPS18 core subunit of CORVET and HOPS complexes
Symbol
vps18 Nomenclature History
Previous Names
  • chunp6929
  • hm:zehl0587
  • wu:fj35h10 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have protein binding activity, bridging. Involved in several processes, including apical protein localization; endosome to pigment granule transport; and notochord cell vacuolation. Predicted to localize to HOPS complex and endosome. Used to study cholestasis. Orthologous to human VPS18 (VPS18 core subunit of CORVET and HOPS complexes).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps18 Human Ortholog
No data available
Associated With vps18 Via Experimental Models
Human Disease Fish Conditions Citations
cholestasis vps18hi2499aTg standard conditions Sadler et al., 2005
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007810 Pep3/Vps18/deep orange
Repeat IPR000547 Clathrin, heavy chain/VPS, 7-fold repeat
Domain Details Per Protein
Protein Length Clathrin, heavy chain/VPS, 7-fold repeat Pep3/Vps18/deep orange
UniProtKB:P59015 974
UniProtKB:B7ZVV5 974
UniProtKB:A8WGL1 974
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations