Gene

sf3b4

ID
ZDB-GENE-020419-22
Name
splicing factor 3b, subunit 4
Symbol
sf3b4 Nomenclature History
Previous Names
  • chunp6902
  • fb36a04
  • wu:fb36a04 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Predicted to be involved in positive regulation of mRNA splicing, via spliceosome. Predicted to localize to U12-type spliceosomal complex and nucleolus. Human ortholog(s) of this gene implicated in Nager acrofacial dysostosis. Orthologous to human SF3B4 (splicing factor 3b subunit 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sf3b4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Nager acrofacial dysostosis Alliance Acrofacial dysostosis 1, Nager type 154400
Associated With sf3b4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR034158 SF3B4, RNA recognition motif 1
Domain IPR034159 SF3B4, RNA recognition motif 2
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain SF3B4, RNA recognition motif 1 SF3B4, RNA recognition motif 2
UniProtKB:Q6NWB3 400
UniProtKB:Q8JGT1 400
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations