Gene

pole2

ID
ZDB-GENE-020419-16
Name
polymerase (DNA directed), epsilon 2
Symbol
pole2 Nomenclature History
Previous Names
  • CHUNP6886
  • polymerase, epsilon 2
  • wu:fb49c03
  • wu:fc49h08
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and DNA-directed DNA polymerase activity. Predicted to be involved in DNA-dependent DNA replication and error-prone translesion synthesis. Predicted to localize to epsilon DNA polymerase complex. Is expressed in several structures, including eye; immature eye; intestinal bulb primordium; neural plate; and ventricular zone. Orthologous to human POLE2 (DNA polymerase epsilon 2, accessory subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pole2 Human Ortholog
No data available
Associated With pole2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007185 DNA polymerase alpha/delta/epsilon, subunit B
Domain IPR024639 DNA polymerase epsilon subunit B, N-terminal
Family IPR016266 DNA polymerase epsilon, subunit B
Domain Details Per Protein
Protein Length DNA polymerase alpha/delta/epsilon, subunit B DNA polymerase epsilon, subunit B DNA polymerase epsilon subunit B, N-terminal
UniProtKB:Q6DGQ3 341
UniProtKB:A8KBP8 527
UniProtKB:A0A0G2KT55 324
UniProtKB:Q8JHG8 527
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations