ZFIN is now using GRCz12tu for Genomic Data
Gene
sall1a
- ID
- ZDB-GENE-020228-2
- Name
- spalt-like transcription factor 1a
- Symbol
- sall1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within embryonic pectoral fin morphogenesis and positive regulation of fibroblast growth factor receptor signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including fin; nervous system; neural keel; neural tube; and tail bud. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome; middle lobe syndrome; and renal Wilms' tumor. Orthologous to human SALL1 (spalt like transcription factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb896 (16 images)
- eu809 (28 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kawakami et al., 2025
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Townes-Brocks syndrome | Alliance | Townes-Brocks branchiootorenal-like syndrome | 107480 |
| Townes-Brocks syndrome | Alliance | Townes-Brocks syndrome 1 | 107480 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sal C2H2-type zinc-finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|
| UniProtKB:A0A1D5NSE4 | InterPro | 1217 | |||
| UniProtKB:F1QI36 | InterPro | 1313 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sall1a-201
(1)
|
Ensembl | 6,552 nt | ||
| mRNA |
sall1a-202
(1)
|
Ensembl | 6,651 nt | ||
| mRNA |
sall1a-203
(1)
|
Ensembl | 3,974 nt | ||
| mRNA |
sall1a-204
(1)
|
Ensembl | 4,091 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers