Gene
meis1a
- ID
- ZDB-GENE-020122-3
- Name
- Meis homeobox 1 a
- Symbol
- meis1a Nomenclature History
- Previous Names
-
- meis4.1a
- meis4.1b
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Is predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including angiogenesis; animal organ development; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within brain development. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; nervous system; pectoral fin bud; pectoral fin musculature; and segmental plate. Orthologous to human MEIS1 (Meis homeobox 1).
- Genome Resources
- Note
-
meis4.1b was merged into meis4.1a because they were splice variants of the same gene according to the original publication by Waskiewicz et al., 2001.
- Comparative Information
-
- All Expression Data
- 10 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65739 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox domain | Homeobox KN domain | Homeobox-like domain superfamily | Homeobox protein PKNOX/Meis, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q7SZP3
|
380 | ||||
|
UniProtKB:Q90XG7
|
149 | ||||
|
UniProtKB:H0WEE7
|
123 | ||||
|
UniProtKB:H0WF09
|
119 | ||||
|
UniProtKB:Q6NZT4
|
380 | ||||
|
UniProtKB:Q90XH0
|
380 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
meis1a-201
(1)
|
2185 nt | |
| mRNA |
meis1a-203
(1)
|
760 nt | |
| mRNA |
meis1a-204
(1)
|
942 nt | |
| ncRNA |
meis1a-003
(1)
|
933 nt |
Interactions and Pathways
No data available
Plasmids
No data available