Gene
gbx1
- ID
- ZDB-GENE-020117-2
- Name
- gastrulation brain homeobox 1
- Symbol
- gbx1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in cerebellum development; midbrain-hindbrain boundary morphogenesis; and regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation. Predicted to localize to nucleus. Is expressed in several structures, including nervous system; neural keel; neural plate; presumptive neural plate; and ventral mesoderm. Orthologous to human GBX1 (gastrulation brain homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 39 figures from 20 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb619 (31 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Rhinn et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox domain, metazoa | Homeobox-like domain superfamily | Homeobox protein GBX-1/2 |
|---|---|---|---|---|---|---|
|
UniProtKB:Q90ZB2
|
316 |
Interactions and Pathways
No data available
Plasmids
No data available