Gene

per2

ID
ZDB-GENE-011220-2
Name
period circadian clock 2
Symbol
per2 Nomenclature History
Previous Names
  • per2a (1)
  • zper2 (1)
  • fj43b09
  • wu:fj43b09
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Enables chromatin binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and locomotor rhythm. Is expressed in heart; liver; muscle; nervous system; and ovary. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome and advanced sleep phase syndrome 1. Orthologous to human PER2 (period circadian regulator 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
30 figures from 20 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With per2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
advanced sleep phase syndrome 1 Alliance ?Advanced sleep phase syndrome, familial, 1 604348
Associated With per2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000014 PAS domain
Domain IPR013655 PAS fold-3
Domain IPR022728 Period circadian-like, C-terminal
Homologous_superfamily IPR035965 PAS domain superfamily
Domain Details Per Protein
Protein Length PAS domain PAS domain superfamily PAS fold-3 Period circadian-like, C-terminal
UniProtKB:Q7T1C9 1404
UniProtKB:B3DJN7 1399
UniProtKB:F1QUT1 1399
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations