Gene
mt-nd2
- ID
- ZDB-GENE-011205-8
- Name
- NADH dehydrogenase 2, mitochondrial
- Symbol
- mt-nd2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: MT Mapping Details/Browsers
- Description
- Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Is expressed in several structures, including digestive system; immature eye; midbrain; musculature system; and segmental plate. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb950 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Complex I Subunit 2 | NADH dehydrogenase subunit 2, C-terminal | NADH:quinone oxidoreductase/Mrp antiporter, transmembrane domain | NADH:ubiquinone oxidoreductase, chain 2 |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0A0V9A1 | InterPro | 348 | ||||
| UniProtKB:Q9MIY9 | InterPro | 348 |
1 - 2 of 2
- Genome Browsers
- No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mt-nd2-201
(1)
|
Ensembl | 1,047 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available