Gene

ywhag1

ID
ZDB-GENE-011115-1
Name
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
Symbol
ywhag1 Nomenclature History
Previous Names
  • ywhag
  • cb47 (1)
  • fd20c02
  • wu:fd20c02
  • wu:fj53d01
  • zgc:73131
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable phosphorylation-dependent protein binding activity; protein kinase C binding activity; and protein sequestering activity. Acts upstream of or within brain development and heart development. Predicted to be active in cytoplasm. Is expressed in head; nervous system; neural tube; otic vesicle; and trigeminal placode. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 56. Orthologous to human YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Komoike et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ywhag1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 56 Alliance Developmental and epileptic encephalopathy 56 617665
1 - 1 of 1
Associated With ywhag1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023409 14-3-3 protein, conserved site
Domain IPR023410 14-3-3 domain
Family IPR000308 14-3-3 protein
Homologous_superfamily IPR036815 14-3-3 domain superfamily
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length 14-3-3 domain 14-3-3 domain superfamily 14-3-3 protein 14-3-3 protein, conserved site
UniProtKB:Q6PC29 InterPro 247
UniProtKB:A1E267 InterPro 247
1 - 2 of 2
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ywhag1-201 (1)
Ensembl
Ensembl 1,374 nt
ZFIN BLAST
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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