Gene
adh5
- ID
- ZDB-GENE-011003-1
- Name
- alcohol dehydrogenase 5
- Symbol
- adh5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity; alcohol dehydrogenase (NAD+) activity; and zinc ion binding activity. Predicted to be involved in formaldehyde catabolic process. Predicted to be active in cytosol. Is expressed in several structures, including blastodisc; central nervous system; digestive system; pleuroperitoneal region; and trunk. Human ortholog(s) of this gene implicated in AMED syndrome and asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77553 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Cox et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| AMED syndrome | Alliance | AMED syndrome, digenic | 619151 |
1 - 1 of 1
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR002328 | Alcohol dehydrogenase, zinc-type, conserved site |
| Domain | IPR013149 | Alcohol dehydrogenase-like, C-terminal |
| Domain | IPR013154 | Alcohol dehydrogenase-like, N-terminal |
| Family | IPR014183 | Alcohol dehydrogenase class III |
| Homologous_superfamily | IPR011032 | GroES-like superfamily |
1 - 5 of 6 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | Alcohol dehydrogenase class III | Alcohol dehydrogenase-like, C-terminal | Alcohol dehydrogenase-like, N-terminal | Alcohol dehydrogenase, zinc-type, conserved site | GroES-like superfamily | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NXA6 | InterPro | 376 |
1 - 1 of 1
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available