Gene
bambia
- ID
- ZDB-GENE-010416-1
- Name
- BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
- Symbol
- bambia Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Is predicted to enable frizzled binding activity. Involved in transforming growth factor beta receptor signaling pathway. Acts upstream of or within dorsal/ventral pattern formation; negative regulation of BMP signaling pathway; and platelet activation. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; germ ring; optic cup; and pectoral fin bud. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human BAMBI (BMP and activin membrane bound inhibitor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb998 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from O'Connor et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009345 | BMP and activin membrane-bound inhibitor |
Domain Details Per Protein
| Protein | Length | BMP and activin membrane-bound inhibitor |
|---|---|---|
|
UniProtKB:Q6IQW1
|
258 | |
|
UniProtKB:Q9DFZ0
|
258 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
bambia-201
(1)
|
1569 nt |
Interactions and Pathways
Plasmids
No data available