Gene
six5
- ID
- ZDB-GENE-010201-3
- Name
- SIX homeobox 5
- Symbol
- six5 Nomenclature History
- Previous Names
-
- six4.3
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Is predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of transcription, DNA-templated. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in branchiootorenal syndrome 2. Orthologous to human SIX5 (SIX homeobox 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu588 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
branchiootorenal syndrome 2 | Alliance | Branchiootorenal syndrome 2 | 610896 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox-like domain superfamily | Homeobox protein SIX1, N-terminal SD domain |
---|---|---|---|---|---|
UniProtKB:F6NWW8
|
798 | ||||
UniProtKB:Q9DEC0
|
797 |
Interactions and Pathways
No data available
Plasmids
No data available