Gene
psmb7
- ID
- ZDB-GENE-001208-4
- Name
- proteasome 20S subunit beta 7
- Symbol
- psmb7 Nomenclature History
- Previous Names
-
- beta2 (1)
- unp311
- zgc:110090
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable endopeptidase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within phosphorylation and proteolysis involved in protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of proteasome core complex, beta-subunit complex. Predicted to be active in cytosol and nucleus. Orthologous to human PSMB7 (proteasome 20S subunit beta 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6892156 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR016050 | Proteasome beta-type subunit, conserved site |
| Domain | IPR024689 | Proteasome beta subunit, C-terminal |
| Family | IPR000243 | Peptidase T1A, proteasome beta-subunit |
| Family | IPR001353 | Proteasome, subunit alpha/beta |
| Family | IPR023333 | Proteasome B-type subunit |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Nucleophile aminohydrolases, N-terminal | Peptidase T1A, proteasome beta-subunit | Proteasome beta subunit, C-terminal | Proteasome beta-type subunit, conserved site | Proteasome B-type subunit | Proteasome, subunit alpha/beta |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PQK9 | InterPro | 286 | ||||||
| UniProtKB:Q7T002 | InterPro | 277 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001045564 (1) | 1041 nt | ||
| Genomic | GenBank:AL772368 (1) | 162620 nt | ||
| Polypeptide | UniProtKB:A0A8M9PQK9 (1) | 286 aa |
- Banu, S., Gaur, N., Nair, S., Ravikrishnan, T., Khan, S., Mani, S., Bharathi, S., Mandal, K., Kuram, N.A., Vuppaladadium, S., Ravi, R., Murthy, C.L.N., Quoseena, M., Babu, N.S., Idris, M.M. (2022) Transcriptomic and proteomic analysis of epimorphic regeneration in zebrafish caudal fin tissue. Genomics. 114(2):110300
- Hasan, A.M., Jyoti, M.M.S., Rana, M.R., Rezanujjaman, M., Tokumoto, T. (2022) Purification and Identification of the 20S Proteasome Complex from Zebrafish. Zebrafish. 19:18-23
- Weeks, O., Miller, B.M., Pepe-Mooney, B.J., Oderberg, I.M., Freeburg, S.H., Smith, C.J., North, T.E., Goessling, W. (2022) Embryonic alcohol exposure disrupts the ubiquitin-proteasome system. JCI insight. 7(23):
- Cahill, T., da Silveira, W.A., Renaud, L., Williamson, T., Wang, H., Chung, D., Overton, I., Chan, S.S.L., Hardiman, G. (2021) Induced Torpor as a Countermeasure for Low Dose Radiation Exposure in a Zebrafish Model. Cells. 10(4):
- Grimholt, U. (2018) Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules. BMC Evolutionary Biology. 18:25
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- McConnell, S.C., Hernandez, K.M., Wcisel, D.J., Kettleborough, R.N., Stemple, D.L., Yoder, J.A., Andrade, J., de Jong, J.L. (2016) Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution. Proceedings of the National Academy of Sciences of the United States of America. 113(34):E5014-23
- Nguyen, V.T., Fuse, Y., Tamaoki, J., Akiyama, S.I., Muratani, M., Tamaru, Y., Kobayashi, M. (2016) Conservation of the Nrf2-Mediated Gene Regulation of Proteasome Subunits and Glucose Metabolism in Zebrafish. Oxidative medicine and cellular longevity. 2016:5720574
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Pei, D.S., Sun, Y.H., Chen, S.P., Wang, Y.P., Hu, W., and Zhu, Z.Y. (2007) Zebrafish GAPDH can be used as a reference gene for expression analysis in cross-subfamily cloned embryos. Analytical biochemistry. 363(2):291-293
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