Gene
stard3
- ID
- ZDB-GENE-001120-2
- Name
- StAR related lipid transfer domain containing 3
- Symbol
- stard3 Nomenclature History
- Previous Names
-
- fc66d12
- mln64-pen
- mln64
- wu:fc66d12 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable cholesterol binding activity and protein homodimerization activity. Predicted to be involved in cholesterol transport and vesicle tethering to endoplasmic reticulum. Predicted to be located in organelle membrane contact site. Predicted to be active in endoplasmic reticulum-endosome membrane contact site and late endosome membrane. Predicted to colocalize with endoplasmic reticulum membrane. Is expressed in yolk syncytial layer. Orthologous to human STARD3 (StAR related lipid transfer domain containing 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63478 (6 images)
- IMAGE:6912334 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | MENTAL domain | StAR-related lipid transfer protein 3, C-terminal | StAR-related Lipid Transfer (STARD3) | START domain | START-like domain superfamily | Steroidogenic acute regulatory protein-like |
---|---|---|---|---|---|---|---|---|
UniProtKB:Q9DFS4 | InterPro | 448 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
stard3-201
(1)
|
Ensembl | 2,756 nt | ||
mRNA |
stard3-202
(1)
|
Ensembl | 642 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-348K1 | ZFIN Curated Data | |
Contained in | BAC | CH211-51M24 | ZFIN Curated Data | |
Encodes | EST | fc66d12 | ZFIN Curated Data | |
Encodes | EST | IMAGE:6912334 | Thisse et al., 2004 | |
Encodes | STS | mln64 | ||
Encodes | cDNA | MGC:63478 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_131662 (1) | 2449 nt | ||
Genomic | GenBank:BX004850 (1) | 121375 nt | ||
Polypeptide | UniProtKB:Q9DFS4 (1) | 448 aa |
- Jia, W., Liang, D., Li, N., Liu, M., Dong, Z., Li, J., Dong, X., Yue, Y., Hu, P., Yao, J., Zhao, Q. (2018) Zebrafish microRNA miR-210-5p inhibits primitive myelopoiesis by silencing foxj1b and slc3a2a mRNAs downstream of gata4/5/6 transcription factor genes. The Journal of biological chemistry. 294(8):2732-2743
- Garcia-Reyero, N., Escalon, L., Prats, E., Faria, M., Soares, A.M., Raldúa, D. (2016) Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Bulletin of environmental contamination and toxicology. 96(6):707-713
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
- Bauer, M.P., Bridgham, J.T., Langenau, D.M., Johnson, A.L., and Goetz, F.W (2000) Conservation of steroidogenic acute regulatory (StAR) protein structure and expression in vertebrates. Molecular and Cellular Endocrinology. 168(1-2):119-125
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