Gene
per3
- ID
- ZDB-GENE-000804-1
- Name
- period circadian clock 3
- Symbol
- per3 Nomenclature History
- Previous Names
-
- period3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable transcription cis-regulatory region binding activity and transcription corepressor binding activity. Acts upstream of or within circadian regulation of gene expression and photoperiodism. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; hematopoietic system; oocyte; red sensitive photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome; advanced sleep phase syndrome 3; and bipolar disorder. Orthologous to human PER3 (period circadian regulator 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pierce et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| advanced sleep phase syndrome 3 | Alliance | ?Advanced sleep phase syndrome, familial, 3 | 616882 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PAS domain | PAS domain superfamily | PAS fold-3 | Period circadian-like, C-terminal | Period circadian protein homolog 1-3, PAS-A domain | Period circadian regulator |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9I8L4 | InterPro | 1281 | ||||||
| UniProtKB:A0A8M1PBM5 | InterPro | 1281 | ||||||
| UniProtKB:A0AB32U1S9 | InterPro | 1260 |
Interactions and Pathways
No data available
Plasmids
No data available