Gene

gart

ID
ZDB-GENE-000616-14
Name
phosphoribosylglycinamide formyltransferase
Symbol
gart Nomenclature History
Previous Names
  • wu:fb33g04 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have phosphoribosylamine-glycine ligase activity and phosphoribosylformylglycinamidine cyclo-ligase activity. Involved in camera-type eye development; chordate embryonic development; and pigmentation. Predicted to localize to cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; nervous system; pigment cell; and yolk syncytial layer. Orthologous to human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gart Human Ortholog
No data available
Associated With gart Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR001555 Phosphoribosylglycinamide formyltransferase, active site
Conserved_site IPR020559 Phosphoribosylglycinamide synthetase, conserved site
Domain IPR002376 Formyl transferase, N-terminal
Domain IPR010918 PurM-like, C-terminal domain
Domain IPR011761 ATP-grasp fold
Domain IPR016188 PurM-like, N-terminal domain
Domain IPR020560 Phosphoribosylglycinamide synthetase, C-domain
Domain IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
Domain IPR020562 Phosphoribosylglycinamide synthetase, N-terminal
Family IPR000115 Phosphoribosylglycinamide synthetase
Family IPR004607 Phosphoribosylglycinamide formyltransferase
Family IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase
Homologous_superfamily IPR011054 Rudiment single hybrid motif
Homologous_superfamily IPR013815 ATP-grasp fold, subdomain 1
Homologous_superfamily IPR016185 Pre-ATP-grasp domain superfamily
Homologous_superfamily IPR036477 Formyl transferase, N-terminal domain superfamily
Homologous_superfamily IPR036676 PurM-like, C-terminal domain superfamily
Homologous_superfamily IPR036921 PurM-like, N-terminal domain superfamily
Homologous_superfamily IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily
Domain Details Per Protein
Protein Length ATP-grasp fold ATP-grasp fold, subdomain 1 Formyl transferase, N-terminal Formyl transferase, N-terminal domain superfamily Phosphoribosylformylglycinamidine cyclo-ligase Phosphoribosylglycinamide formyltransferase Phosphoribosylglycinamide formyltransferase, active site Phosphoribosylglycinamide synthetase Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Phosphoribosylglycinamide synthetase, C-domain Phosphoribosylglycinamide synthetase, C-domain superfamily Phosphoribosylglycinamide synthetase, conserved site Phosphoribosylglycinamide synthetase, N-terminal Pre-ATP-grasp domain superfamily PurM-like, C-terminal domain PurM-like, C-terminal domain superfamily PurM-like, N-terminal domain PurM-like, N-terminal domain superfamily Rudiment single hybrid motif
UniProtKB:Q9I9E6 1017
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations